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Pressure BioSciences Inc

PBIO OTC

Wall Street Researcher – Research Report – Pressure Biosciences Inc.

Must See Corp Video

Pressure BioSciences Shatters Preconceived Nanoemulsion Stability, Performance, and Production Limits: Produces CBD Oil Nanoemulsions with 18 Month Stability

The company intends to hold a special shareholders meeting on Dec 30, 2021 at 4 PM EDT at the corporate headquarters. An up to date screen shot of PBIO’s present condition can be found In the Proxy BELOW

PROXY STATEMENT

These shares have consolidated recently due to holiday market conditions and slowing stock market activities. This may be the right time to take advantage of the slow trading in the shares of PBIO. We continue to  anticipate a BREAKOUT above the $4.50 level.

Much is happening and many traders are not taking advantage of bargain price levels due to tax selling and holiday malaise

A quick bounce back to normal levels is predicted after Dec 22, 2021

Watch this compelling video explaining in detail the products and medical devices that Pressure Bio Sciences offers the medical and scientific community  Must See Corp Video .

Investor Contact – Gary Zwetchkenbaum- Plum Tree Consulting LLC –Cell :    516 – 455-7662 – EMAIL – gzplumtree@gmail.com

Pressure BioSciences Shatters Preconceived Nanoemulsion Stability, Performance, and Production Limits: Produces CBD Oil Nanoemulsions with 18 Month Stability

UST Platform’s Ultra-low Droplet Sizes and Test Verified Stability Portends Revolution in Major Markets

SOUTH EASTON, MA / ACCESSWIRE / December 22, 2021 / Pressure BioSciences, Inc. (OTCQB:PBIO) (“PBI” or the “Company”), a leader in the development and sale of broadly enabling, pressure-based instruments, consumables, and innovative services to the worldwide biotechnology, biotherapeutics, cosmetics, nutraceuticals, agrochemical, and food & beverage industries, today announced that hemp-derived cannabidiol (“CBD”) processed with its patented Ultra Shear Technology™ (“UST™”) platform produced high-quality water-soluble nanoemulsions of CBD oil in water that have now demonstrated rock-solid visual and analytical stability 18 months after production and baseline testing.

CBD is a widely popular therapeutic for relief of anxiety, depression, and PTSD, as well as chronic inflammatory and neuropathic pain. It is FDA-approved for use in the control of epileptic seizures in Lennox-Gastaut syndrome and Dravet syndrome. Early research suggests that CBD reduces spasticity in multiple sclerosis and may lessen the severity of neurological symptoms associated with Alzheimer’s Disease, Parkinson’s disease, and schizophrenia. CBD is under investigation as a palliative adjunctive therapy in cancer.

However, CBD is insoluble in water and is poorly absorbed by the human body. The World Health Organization (WHO) estimates that as little as 6% of CBD is absorbed via current oral delivery routes. Thus, most ingested CBD is wasted, passing through the body without being absorbed. Consequently, there is enormous interest in the development of truly water-soluble CBD to deliver efficient dosing, absorption, bioavailability, and benefit from CBD products (e.g., foods and beverages, therapeutics).

Dr. Alexander V. Lazarev, Chief Science Officer of PBI, explained: “Nanoemulsions, liposomes, and solid lipid nanoparticles present many exciting opportunities as pharmaceutical and nutraceutical delivery systems. The smaller the size of oil droplets or particles the better the stability and bioavailability of these preparations. Once the droplets/particles reach below about 100 nanometers, nanoemulsions appear optically clear and remain stable for months or even years, thus maintaining their aesthetic appeal, bioavailability, and importantly, their shelf life. Moreover, these preparations can be filter-sterilized to comply with FDA requirements for injectable drugs. Today we are pleased to announce that our enabling, affordable, and scalable UST process has been shown to create nanoemulsions that maintain rock-solid stability, excellent water solubility, and pristine visual clarity at room temperature for at least 18 months. These results offer the potential to significantly increase shelf-life and effectiveness for CBD and a multitude of other oil-based products in use today.”

Mr. Gary B. Smejkal, Senior Research Scientist at PBI, explained the Company’s breakthrough: “The intense fluid shearing in UST progressively decreases oil droplet size with each cycle, making the method highly tunable while enabling the user to select and reliably reach a target droplet size. We have demonstrated that our platform consistently produces CBD nanoemulsions of uniform 30-40 nm droplet sizes that are stable at room temperature for at least 18 months. Measurements of droplet size by Dynamic Light Scattering (DLS) over time courses at various temperatures have shown that particle size remains unchanged over prolonged storage at room temperature or refrigeration, a major indication of nanoemulsion stability. Clarity, quantified by UV/Vis spectroscopy, also remains unchanged for equally long periods of time, making the CBD nanoemulsion visually undetectable when infused into bottled water or other beverages.”

To view a short video of PBI’s innovative UST platform for the preparation of CBD nanoemulsions, click here.

Mr. John B. Hollister, Director of Sales and Marketing at PBI, forecasted: “Nanoemulsions of CBD oil created by our patented UST processing platform offer the potential to revolutionize the rapidly growing cannabis market in food/beverages and therapeutics. But CBD is only a microcosm of the revolution we believe the UST platform promises to deliver for a vast array of products spanning multiple major markets, including therapeutics, nutraceuticals, agrochem, cosmetics, and food/beverages. From truly clear, water-soluble infusions in beverages with long-term stability (cold or room temp), to predictable dosing with much faster onset of action than other oral/topical forms, we believe the benefits, appeal, and adoption by consumers will be tremendous. This historic milestone in surpassing all 18-month stability goals positions PBI for rapid customer adoption of our UST nanoemulsion systems upon commercial release planned in the first half of 2022.”

With a projected compounded annual growth rate (CAGR) of 21.2% from 2021 to 2028, the global CBD market is expected to grow from USD $2.8B in 2020 to USD $13B in 2028.

About Pressure BioSciences, Inc.

Pressure BioSciences, Inc. (OTCQB: PBIO) is a leader in the development and sale of innovative, broadly enabling, pressure-based solutions for the worldwide life sciences and other industries. Our products are based on the unique properties of both constant (i.e., static) and alternating (i.e., pressure cycling technology, or PCT) hydrostatic pressure. PCT is a patented enabling technology platform that uses alternating cycles of hydrostatic pressure between ambient and ultra-high levels to control bio-molecular interactions safely and reproducibly (e.g., cell lysis, biomolecule extraction). Our primary focus is the development of PCT-based products for biomarker and target discovery, drug design and development, biotherapeutics characterization and quality control, soil & plant biology, forensics, and counter-bioterror applications. Additionally, major new market opportunities have emerged in the use of our pressure-based technologies in the following areas: (1) the use of our recently acquired, patented technology from BaroFold, Inc. (the “BaroFold” technology) to allow entry into the bio-pharma contract services sector, and (2) the use of our recently-patented, scalable, high-efficiency, pressure-based Ultra Shear Technology (“UST”) platform to (i) create stable nanoemulsions of otherwise immiscible fluids (e.g., oils and water) and to (ii) prepare higher quality, homogenized, extended shelf-life or room temperature stable low-acid liquid foods that cannot be effectively preserved using existing non-thermal technologies.

Forward Looking Statements

This press release contains forward-looking statements. These statements relate to future events or our future financial performance and involve known and unknown risks, uncertainties and other factors that may cause our or our industry’s actual results, levels of activity, performance, or achievements to be materially different from any future results, levels of activity, performance or achievements expressed, implied, or inferred by these forward-looking statements. In some cases, you can identify forward-looking statements by terminology such as “may,” “will,” “should,” “could,” “would,” “expects,” “plans,” “intends,” “anticipates,” “believes,” estimates,” “predicts,” “projects,” “potential” or “continue” or the negative of such terms and other comparable terminology. These statements are only predictions based on our current expectations and projections about future events. You should not place undue reliance on these statements. In evaluating these statements, you should specifically consider various factors. Actual events or results may differ materially. These and other factors may cause our actual results to differ materially from any forward-looking statement. These risks, uncertainties, and other factors include, but are not limited to, the risks and uncertainties discussed under the heading “Risk Factors” in the Company’s Annual Report on Form 10-K for the year ended December 31, 2020, and other reports filed by the Company from time to time with the SEC. The Company undertakes no obligation to update any of the information included in this release, except as otherwise required by

Operational and Technical Achievements Set Stage for Expected Major Growth and Profitability in 2022

Investor Call Scheduled for Wednesday, November 17, 2021 at 4:30 p.m. ET

SOUTH EASTON, MA / ACCESSWIRE / November 17, 2021 / Pressure BioSciences, Inc. (OTCQB:PBIO) (“PBI” or the “Company”), a leader in the development and sale of broadly enabling, pressure-based instruments, consumables, and platform technology solutions to the worldwide biotechnology, biotherapeutics, nutraceuticals, cosmetics, agriculture, and food & beverage industries, today reported financial results for the third quarter ended September 30, 2021, provided a business update, and offered guidance for an expected strong 2022.

Financial Highlights: Q3 2021 vs. Q3 2020 (rounded to nearest hundred except EPS)

• Total revenue for Q3 2021 was $518,000 compared to $534,000 for the Q3 2020, a decrease of 3%.
• Instrument sales for Q3 2021 were $274,200 compared to $312,700 for Q3 2020, a decrease of 12%.
• Consumable sales for Q3 2021 were $46,000 compared to $49,000 for Q3 2020, a decrease of 7%.
• BaroFold/UST services in Q3 2021 were $99,700 compared to $84,200 for Q3 2020, an increase of 18%.
• New PBI Agrochem subsidiary had initial sales in Q3 2021 of $17,210 (no sales in Q3 2020).
• Operating loss for Q3 2021 was $1,243,000 compared to $819,000 for Q3 2020, an increase of 51%.
• Basic and diluted net loss per share was $(0.82) for Q3 2021 improved from $(1.02) for Q3 2020.

Financial Results: September 2021 YTD vs. September 2020 YTD (rounded to nearest hundred except EPS)

• Total revenue for Sept 2021 YTD was $1,687,000 compared to $1,056,000 for Sept 2020 YTD, a 60% increase.
• Instrument sales for Sept 2021 YTD were $989,500 compared to $568,500 for Sept 2020 YTD, a 74% increase.
• Consumable sales for Sept 2021 YTD were $191,400 compared to $156,200 for Sept 2020 YTD, a 23% increase.
• BaroFold/UST services for Sept 2021 YTD were $241,800 vs. $128,100 for Sept 2020 YTD, an 89% increase.
• Operating loss for Sept 2021 YTD was $(2,964,000) vs. $(3,544,000) for Sept 2020 YTD, a 37% improvement.
• Basic and diluted net loss per share was $(3.02) for Sept 2021 YTD improved from $(4.22) for Sept 2020 YTD.

Mr. John B. Hollister, Director of Sales and Marketing for PBI, commented: “Despite supply chain issues adversely affecting operations, our Q3 2021 financial results were effectively on par with the strong results of Q3 2020. Importantly, our 2021 YTD financial results – including total revenue, instrument & consumable sales, and BaroFold/UST services – maintained our strong improvement trend compared to the same 9-month period in 2020. Significantly, anticipation for our eco-friendly agrochemical product sales in Q4 2021, followed by the release of our much-anticipated UST platform for leasing and licensing in the early part of 2022 continues to build. We are receiving numerous unsolicited calls every week from a variety of markets regarding our product introduction timetable to help deliver better nanoemulsified products via the UST process. We are very excited about the expected impact we believe our UST platform release will have in 2022.”

Q3 2021 Operational and Technical Highlights

• Set up a U.S. warehousing, processing, and product packaging facility for our new PBI Agrochem subsidiary.
• Reported the successful UST nanoemulsification processing of Astaxanthin and Neem Oil.
• UST processed nanoemulsions of CBD oil in water soared past our one-year stability goal – now at 18 months.
• Enacted strategic expansion of BaroFold refolding program with successful debut of instrument sale/lease program.
• Announced plans to set-up Toll Manufacturing partnerships on the east and west U.S. coasts.
• Unveiled aggressive goals for Q4 2021 & FY 2022, including NASDAQ/NYSE Uplist, Agrochem Acquisition, and Profitability.

Mr. Richard T. Schumacher, President and CEO of PBI, commented: “The many successes of the 2021 third quarter have set the stage for continued foundation building in Q4, in preparation for anticipated major growth in 2022. We believe our achievements in Q4 2021 and FY 2022 will be many, and will include: (i) significant increases in agrochem revenue; (ii) shipment of the industrial-scale UST system to our partner The Ohio State University (“OSU”); (iii) announcement of progress made by the OSU/PBIO Consortium leveraging UST for improved food quality, safety and stability; (iv) commercial release of the UST platform; (v) executed fee-for-service contracts for UST toll processing; (vi) up-listing of PBIO to a national stock exchange; and (vii) profitability by or before the end of 2022. Our team and our partners are highly motivated by PBI’s recent successes and strengthening, but we believe the best is yet to come.”

About Pressure BioSciences, Inc.
Pressure BioSciences, Inc. (OTCQB: PBIO) is a leader in the development and sale of innovative, broadly enabling, pressure-based solutions for the worldwide life sciences industry. Our products are based on the unique properties of both constant (i.e., static) and alternating (i.e., pressure cycling technology, or PCT) hydrostatic pressure. PCT is a patented enabling technology platform that uses alternating cycles of hydrostatic pressure between ambient and ultra-high levels to control bio-molecular interactions safely and reproducibly (e.g., cell lysis, biomolecule extraction). Our primary focus is the development of PCT-based products for biomarker and target discovery, drug design and development, biotherapeutics characterization and quality control, soil & plant biology, forensics, and counter-bioterror applications. Additionally, major new market opportunities have emerged in the use of our pressure-based technologies in the following areas: (1) the use of our recently acquired, patented technology from BaroFold, Inc. (the “BaroFold” technology) to allow entry into the bio-pharma contract services sector, and (2) the use of our recently-patented, scalable, high-efficiency, pressure-based Ultra Shear Technology (“UST”) platform to (i) create stable nanoemulsions of otherwise immiscible fluids (e.g., oils and water) and to (ii) prepare higher quality, homogenized, extended shelf-life or room temperature stable low-acid liquid foods that cannot be effectively preserved using existing non-thermal technologies.

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